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Preclinical studies further indicate that RBP4-targeting oligonucleotides effectively decrease RBP4 expression in hepatic and adipose tissues, lower circulating RBP4 levels, and improve IR and hyperglycemia in high-fat-diet animal models (182) (Table 4)
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The French chemist Chevreul (1823) [1], a pioneer of lipid chemistry, believed this sweet-tasting material to be an alcohol and named it ‘glycerin’ (glycerol)
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