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Researchers also identified other downstream effectors of PI3Kp110α signaling, such as Rac, which are involved in promoting cell migration (112)
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In a PD mouse model induced by intraperitoneal injection of salsolinol (SAL), and in SAL-treated SH-SY5Y cells, GSH expression was significantly reduced, whereas levels of ROS, Fe 2+ , ACSL4, MDA, 4-HNE, and α-Syn were markedly elevated
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