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Pharmacological interventions through the use of NOX inhibitors, including diphenyleneiodonium and GKT137831, have demonstrated that inhibiting NOX4 can substantially reduce ROS levels and lipid peroxidation, and thus protect against ferroptosis (109,110)
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For the purposes of this review, only the third hypothesis will be discussed, as it provides a link between H 2 S and the protective effects of NAC
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