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However, when discussing the results of the aforementioned study, it must be emphasized that the study was completed by merely 52% of the patients (62 out of a total 100), which could have affected the results of the study [83] (Table 2)

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In addition to directly damaging the lung, oxidative stress contributes to the proteinase-antiproteinase imbalance both by inactivating antiproteinases (such as alpha-1 antitrypsin and SLPI) and by activating proteinases (such as MMPs)