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It downregulates microRNA-27b-3p (miR-27b-3p), an important epigenetic regulator of TGF-β-induced fibroblast activation and extracellular matrix deposition, leading to suppression of ectopic stromal cell proliferation, inhibition of MMP-9-mediated invasion, and reduction of collagen I/III and α-SMA accumulation (Ritchie et al., 2026)
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